Evaluation of the Urinary Kidney Injury Molecule-1 Levels in Patients With Diabetic Nephropathy

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Evaluation of the urinary kidney injury molecule-1 levels in patients with diabetic nephropathy.

PURPOSE Kidney Injury Molecule-1 is a protein that increases in urine following tubular damage. Kidney Injury Molecule-1 levels were correlated with the level of chronic kidney disease secondary to diabetic nephropathy in patients with type 2 Diabetes Mellitus. METHODS Clinical and laboratory findings of 142 patients with diabetic nephropathy and 34 control subjects were analysed. Creatinine ...

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Urinary kidney injury molecule-1 in patients with IgA nephropathy is closely associated with disease severity.

BACKGROUND The pathological characteristics of IgA nephropathy (IgAN) are highly variable. Urinary kidney injury molecule-1 (KIM-1) is a sensitive biomarker for proximal tubule injury. The aim of the study is to investigate the value of KIM-1 as a biomarker for assessing the renal injury in IgAN. METHODS The levels of urinary KIM-1 in 202 patients with IgAN, 46 patients with other renal disea...

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Kidney injury molecule-1 as a predicting factor for inflamed kidney, diabetic and diabetic nephropathy Egyptian patients

BACKGROUND Kidney injury molecule-1 (KIM-1), a recently discovered transmembrane protein, is expressed in dedifferentiated proximal renal tubular epithelial cells in damaged regions. Kidney injury early detection in diabetic patients has great importance for therapy and prognosis. Therefore, the aim of the present study is to predict, validate and evaluate the presence of KIM-1 in kidney inflam...

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ژورنال

عنوان ژورنال: Clinical & Investigative Medicine

سال: 2014

ISSN: 1488-2353

DOI: 10.25011/cim.v37i6.22242